gastroplustm software (Simulations Plus Inc)
90
Structured Review
Simulations Plus Inc
gastroplustm software
Gastroplustm Software, supplied by Simulations Plus Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gastroplustm+software/gastroplustm+software/pm40281717-76-0-7
Average 90 stars, based on 1 article reviews
Gastroplustm Software, supplied by Simulations Plus Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gastroplustm+software/gastroplustm+software/pm40281717-76-0-7
Average 90 stars, based on 1 article reviews
gastroplustm software - by Bioz Stars,
2026-11
90/100 stars
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In Silico:Article Title: Use of In silico Methodologies to Predict the Bioavailability of Oral Suspensions: A Regulatory Approach. Article Snippet: Laboratory of Molecular Modeling & QSAR, Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Laboratory of Cell Culture (LabCel), Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Laboratory of Pharmaceutical Industrial Technology (LabTIF), Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil Article Title: Quercetin‐encapsulated magnetoliposomes: Fabrication, optimization, characterization, and antioxidant studies Article Snippet: Funding information Birla Institute of Technology, Grant/Award Number: GO/Estb/Ph.D/IRF/2019-20/6649 Abstract Quercetin (QU) faces challenges in its therapeutic efficacy due to its hydrophobic nature and limited oral bioavailability.. Using a Box–Behnken design (BBD) approach, we developed QU-loaded magnetoliposomes (QMLs) to address these limitations.. By encapsulating QU within iron oxide nanoparticles (IONPs) and liposomes (LPs), we enhanced its hydrophilicity and improved its potential for drug delivery. Selection:Article Title: Use of In silico Methodologies to Predict the Bioavailability of Oral Suspensions: A Regulatory Approach. Article Snippet: Laboratory of Molecular Modeling & QSAR, Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Laboratory of Cell Culture (LabCel), Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Laboratory of Pharmaceutical Industrial Technology (LabTIF), Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil Software:Article Title: Use of In silico Methodologies to Predict the Bioavailability of Oral Suspensions: A Regulatory Approach. Article Snippet: Laboratory of Molecular Modeling & QSAR, Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Laboratory of Cell Culture (LabCel), Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Laboratory of Pharmaceutical Industrial Technology (LabTIF), Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil Article Title: Quercetin‐encapsulated magnetoliposomes: Fabrication, optimization, characterization, and antioxidant studies Article Snippet: Funding information Birla Institute of Technology, Grant/Award Number: GO/Estb/Ph.D/IRF/2019-20/6649 Abstract Quercetin (QU) faces challenges in its therapeutic efficacy due to its hydrophobic nature and limited oral bioavailability.. Using a Box–Behnken design (BBD) approach, we developed QU-loaded magnetoliposomes (QMLs) to address these limitations.. By encapsulating QU within iron oxide nanoparticles (IONPs) and liposomes (LPs), we enhanced its hydrophilicity and improved its potential for drug delivery. Article Title: RSM and AI based machine learning for quality by design development of rivaroxaban push-pull osmotic tablets and its PBPK modeling Article Snippet: Using Minitab® 20 (Minitab, LLC, Pennsylvania, USA), shelf life was calculated after determining the percentage drug assay and all the critical parameters (Y1–Y4) . .. The systemic disposition of rivaroxaban from the optimized formulation (F pred ) was predicted using the ‘Advanced Compartmental Absorption and Transit’ (ACAT ®) model embedded in Article Title: Integrated in vitro – In vivo – In silico studies in the pharmaceutical development of propranolol hydrochloride mucoadhesive buccal films Article Snippet: In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have been developed.. 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Since non-selective NSAIDs are not well-tolerated post-surgery, selective cyclooxygenase-2 (COX-2) inhibitors may be important for these patients.. In this work we investigated celecoxib, etoricoxib and etodolac, for impaired post-bariatric solubility/dissolution and absorption. Formulation:Article Title: RSM and AI based machine learning for quality by design development of rivaroxaban push-pull osmotic tablets and its PBPK modeling Article Snippet: Using Minitab® 20 (Minitab, LLC, Pennsylvania, USA), shelf life was calculated after determining the percentage drug assay and all the critical parameters (Y1–Y4) . .. The systemic disposition of rivaroxaban from the optimized formulation (F pred ) was predicted using the ‘Advanced Compartmental Absorption and Transit’ (ACAT ®) model embedded in Article Title: In Vitro-In Silico Approach in the Development of Clopidogrel Solid Dispersion Formulations. Article Snippet: .. Clinical Proteomics:Article Title: Integrated in vitro – In vivo – In silico studies in the pharmaceutical development of propranolol hydrochloride mucoadhesive buccal films Article Snippet: In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have been developed.. The aim of this study was the development, pharmaceutical-technological (uniformity of mass and drug content, film thickness, potential interactions between polymers and propranolol hydrochloride, in vitro drug permeation and drug release, mechanical and mucoadhesive properties), and biopharmaceutical characterization of prepared mucoadhesive buccal films through conducting in vivo study in spontaneously hypertensive rats and in silico modeling of intraoral and gastrointestinal drug absorption.. 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Concentration Assay:Article Title: Integrated in vitro – In vivo – In silico studies in the pharmaceutical development of propranolol hydrochloride mucoadhesive buccal films Article Snippet: In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have been developed.. The aim of this study was the development, pharmaceutical-technological (uniformity of mass and drug content, film thickness, potential interactions between polymers and propranolol hydrochloride, in vitro drug permeation and drug release, mechanical and mucoadhesive properties), and biopharmaceutical characterization of prepared mucoadhesive buccal films through conducting in vivo study in spontaneously hypertensive rats and in silico modeling of intraoral and gastrointestinal drug absorption.. For in vivo study formulation F2 (hydroxypropylmethyl cellulose 0.5%, polyethylene oxide 3.5%, polyvinyl alcohol 1.5%, propylene glycol 3%, and propranolol hydrochloride 2%) was selected, which showed the highest values of tensile strength and percentage of elongation, as well as the highest value of the force of adhesion. Article Title: Selective COX-2 inhibitors after bariatric surgery: Celecoxib, etoricoxib and etodolac post-bariatric solubility/dissolution and pharmacokinetics. Article Snippet: Anatomical/physiological gastrointestinal changes after bariatric surgery may influence the fate of orally administered drugs.. Since non-selective NSAIDs are not well-tolerated post-surgery, selective cyclooxygenase-2 (COX-2) inhibitors may be important for these patients.. In this work we investigated celecoxib, etoricoxib and etodolac, for impaired post-bariatric solubility/dissolution and absorption. 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